Cystic Fibrosis and Gene Therapy Essay -- Science Genetics Biology Pap

Cystic Fibrosis and constituent TherapyThe average life span of a soulfulness with Cystic Fibrosis is 25-30 years of age. Although the more traditional treatments of this indisposition atomic number 18 adequate, is thither something else that could be even better? Gene therapy is fast becoming adept of the more studied aspects of agenttics today. Lets take a look at some details of Cystic Fibrosis and ingredient therapy.Technical AspectsCystic Fibrosis (CF) is the about common fatal genetic disease in the United States today. CF is an autosomal recessive disease that occurs approximately ace out of 3,300 reside births (Cystic Fibrosis Foundation, 1998). Autosomal means that the gene for CF is not carried on the invoke chromosomes and males and females are both afflicted by this disease. Recessive inheritance is when both parents carry the abnormal gene in their DNA but they themselves do not show evidence of the disease. The mother and father have one normal gene and one a bnormal gene and dont show signs of disease because the normal gene dominates the abnormal gene. To have CF, a child mustiness inherit two abnormal genes, one from each parent. Remember that chromosomes are made up of DNA or deoxyribonucleic acid. DNA is made up of genes, and genes are made up of building blocks called base pairs. The specific gene responsible for CF was identified in 1989 on human chromosome 7 (Pseudomonas Genome Project, 1998). A mutation, or change in the genetic material, resulting in a substitution or loss of one of the base pairs causes the CF gene to be abnormal (Cystic Fibrosis Foundation, 1995).CF does not affect all battalion the same way. The basic problem for all patients however is an abnormality in glands, which produce mucus or sweat. The mucus produced by people... ...ctsabo.htmhttp//www.cff.org/factsabo.htm Cystic Fibrosis Foundation, Gene Therapy. Obtained from the entanglement 10/31/98 http//www.cff.org/genether.htm Genentech Incorporated, Gen e Therapy-An Overview. Obtained from the entanglement 10/31/98 http//www.gene.com/AE/AB/IWT/Gene_Therapy_Overview.html McClean, Phillip. Variation in Chromosome Structure. Obtained from the WWW 10/15/98 http//www.ndsu.nodak.edu/instruct/mcclean/plsc431/chromstruct/chrmo2.htm Pseudomonas Genome Project, Cystic Fibrosis. Obtained from the WWW 10/31/98 http//www.pseudomonas.com/cystic_fibrosis.html Cystic Fibrosis Foundation, An Introduction to Cystic Fibrosis for Patients and Families in Respiratory Diseases and Disorders Sourcebook. Health Reference Series, V. 6, 1995. Sect. 5.1, p. 240. WWWebster Dictionary. Obtained from the WWW 11/2/98 http//www.m-w.com/